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PROpel Phase III trial positive results of Lynparza plus abiraterone in 1st-line metastatic castration-resistant prostate cancer published in New England Journal of Medicine Evidence

Results from the PROpel Phase III trial showed that AstraZeneca and MSD’s Lynparza (olaparib) in combination with abiraterone significantly improved radiographic progression-free survival (rPFS) versus abiraterone alone as a 1st-line treatment for patients with metastatic castration-resistant prostate cancer ...
United Kingdom United States Noel Clarke Eliav Barr Cristian Massacesi Company On Twitter

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Evusheld significantly prevented COVID-19 disease progression or death in TACKLE Phase III treatment trial

Detailed results from the TACKLE Phase III outpatient treatment trial showed AstraZeneca’s Evusheld (tixagevimab and cilgavimab, formerly AZD7442) provided clinically and statistically significant protection against progression to severe COVID-19 or death from any cause compared to placebo, with treatment with ...
United Kingdom United States Great Britain Nat Microbiol Tixagevimab Cilgavimab Hugh Montgomery

[Full text] Immunotherapeutics for Ebola virus Disease

Taï Forest ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus (BDBV), and Bombali ebolavirus. Filoviruses are pleomorphic in shape and possess a lipid envelope. The viral genome is a negative-sense single strand RNA which is approximately 19 kb in size. Since the first outbreak in 1976, EBOV has resurfaced a multitude of times in Africa. Initially, it was responsible for causing small, localized outbreaks until 2013, when the large multinational epidemic was recorded causing 28,646 infectio...
Democratic Republic Of The Congo Democratic Republic Of The General Nat Microbiol Gen Virol Bryan Kissinger Regional Office For Africa

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