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Universal Donor Lungs Generated from Blood Group A Using Gut Enzymes

Using gut enzymes identified in an earlier study that convert group A red blood cells to group O, by cleaving off sugars from A and B antigens, a new study has developed a system to perfuse donor lungs ex vivo to convert lungs from blood type A to O. The new findings could potentially improve fairness in lung allocation, and reduce wait times for transplantation, decreasing mortality for patients on waitlists.
United Kingdom Stephen Withers Marcelo Cypel Naizhou Wang University Of Alberta Department Of Surgery

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