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Scientists Discover How Dengue Vaccine Fails to Protect Against Disease

Scientists Discover How Dengue Vaccine Fails to Protect Against Disease June 23, 2021 UNC School of Medicine scientists led by Aravinda de Silva, PhD, identified the small subpopulation of antibodies in vaccinated children that correlate with protection against dengue fever. This research should help shape better vaccines for one of the most widespread infectious diseases in the world. Aravinda de Silva, PhD CHAPEL HILL, NC – Developing a viable vaccine against dengue virus has proved difficu...
United States Sanofi Pasteur Sandra Henein Cameron Adams School Of Medicine Department Of Microbiology

Not just a phase for RNAS

 E-Mail IMAGE: Image shows cells with oil droplet-like NORAD-Pumilio bodies in red and nucleus in blue. Credit: Mahmoud Elguindy view more  Credit: Mahmoud Elguindy DALLAS - June 9, 2021 - A phenomenon in which an RNA named NORAD drives a protein named Pumilio to form liquid droplets in cells, much like oil in water, appears to tightly regulate the activity of Pumilio. A new study led by UT Southwestern scientists suggests that such RNA-driven "phase separation," in turn, protects aga...
United States F Andrew Bell Steven Mcknight Mar Nell Joshua Mendell Michael Rosen

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UTSW Student Named TMA Student of Year - Focus Daily News

Focus Daily News 2021 Texas Medical Association Medical Student Section (TMA-MSS) Student of the Year Award Whitney Stuard, a sixth-year MD/PhD student in the Medical Scientist Training Program at UT Southwestern Medical School (UT Southwestern), received the 2021 Texas Medical Association Medical Student Section (TMA-MSS) Student of the Year Award. TMA’s House of Delegates policymaking body announced Ms. Stuard’s award today during TexMed, TMA’s annual conference, held virtually. “The ...
Dallas County United States Tanooha Veeramachaneni Sarah Miller Tina Zhu Whitney Stuard

Dual degrees shape research interests for IST assistant professor

IMAGE: Jessica Hallman Silverman, who joined the College of Information Sciences and Technology last year as an assistant professor with a focus in biomedical statistics, made global headlines last summer for his study suggesting that 80% of U.S. COVID-19 cases went undetected in March 2020. He and his research team analyzed data from the Centers for Disease Control and Prevention (CDC) on the number of patients who sought medical care for influenza-like illnesses during that time span. That nu...
New York United States Montana State University North Carolina University Of North Carolina Duke University
Source: psu.edu

Socioeconomic Disparities Associate With Epigenetics and Heart Failure Outcomes

Previously, Wende’s group assisted in a study that identified links between DNA methylation in all cause heart failure associated with the ability to use different metabolic fuels to maintain contractility, namely a decrease in oxidative metabolism.[2] An additional study from the group found molecular mechanisms specific to ischemic heart failure, which identified a key epigenetic regulator (i.e. EZH2) as likely having an active role in gene expression regulation involved in both metabolic a...
United States Marke Pepin Jacques Kpodonu Adamr Wende Kim Allan Williams Roxana Mehran

Study sheds light on how tau aggregates promote Alzheimer's disease

Study sheds light on how tau aggregates promote Alzheimer’s disease Look deep inside the brain of someone with Alzheimers disease, most forms of dementia or the concussion-related syndrome known as chronic traumatic encephalopathy (CTE) and youll find a common suspected culprit: stringy, hairball-like tangles of a protein called tau. Such conditions, collectively known as "tauopathies" strike scores of people across the globe, with Alzheimers alone affecting six million people in the United S...
United States Alois Alzheimer Evan Lester Troy Parker Emily Henderson Scientist Training Program

How tangled proteins kill brain cells, promote Alzheimer's, CTE

 E-Mail Look deep inside the brain of someone with Alzheimers disease, most forms of dementia or the concussion-related syndrome known as chronic traumatic encephalopathy (CTE) and youll find a common suspected culprit: stringy, hairball-like tangles of a protein called tau. Such conditions, collectively known as "tauopathies" strike scores of people across the globe, with Alzheimers alone affecting six million people in the United States. But more than a century after German psychiatrist Alo...
United States Alois Alzheimer Evan Lester Troy Parker Scientist Training Program A University Of Colorado Boulder

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