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TSLP shapes the pathogenic responses of memory CD4+ T cells in eosinophilic esophagitis

TSLP shapes the pathogenic responses of memory CD4+ T cells in eosinophilic esophagitis
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American
Serpin-pharm
Astra-zeneca
Ellodi-pharma
Revolo-biotherapeutics
Regeneron-sanofi
National-institute-of-diabetes
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Cincinnati-center

Benralizumab reduces eosinophils but does not improve eosinophilic gastritis

Treatment with benralizumab induced histological remission, defined as an absence of tissue eosinophilia, among patients with eosinophilic gastritis, according to a study published in The Lancet Gastroenterology & Hepatology.But the persistence of signs, symptoms and biomarkers of the disease during treatment suggested a pathogenic mechanism independent of eosinophil levels in many patients,

Israel
Cincinnati
Ohio
United-states
Kristen-dowd
Gastroenterol-hepatol
Tucker-ellis
Serpin-pharm
Byrichard-gawel
Revolo-biotherapeutics
Marce-rothenberg
Food-allergy-fund

Dupilumab Shows Benefits in Larger EoE Cohort

In a phase 3 trial of adults and adolescents with hard-to-treat eosinophilic esophagitis, 6 months of weekly dupilumab sent 59% of participants into disease remission.

Phoenix
Arizona
United-states
Ohio
Cincinnati
Akron
American
Regeneron-sanofi
Marc-rothenberg
Brian-schroer
Eli-lilly
Serpin-pharm

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