Cleveland Clinic researchers have used nanoparticles to develop a potential vaccine candidate against Dabie Bandavirus, formerly known as Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV), a tick-borne virus that currently has no prevention, treatment or cure.
The patent-pending vaccine uses nanoparticles to carry the antigens that contain instructions for fighting off a virus. Nanoparticle vaccines are designed to effectively deliver antigens at a lower dose with fewer side effects for at-risk groups – including adults over age 50, who are the most vulnerable to SFTSV and the most susceptible to vaccine side effects.
Promising Nanoparticle Vaccine Battles Emerging Tick-Borne Virus
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Nanoparticle vaccine candidate shows promise against emerging tick-borne virus in early studies
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A woman contracted Severe Fever with Thrombocytopenia Syndrome, a tick-borne disease, after coming into contact with a stray cat in Seogipo-si, Jeju, health authorities said on Monday. SFTS is an infectious disease that emerged from China with a mortality rate of up to 17 percent in Korea. The condition has no cure or vaccine as of now. The first local case was reported in 2013, and a total of 608 people have been in.