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Alnylam Pharmaceuticals, Inc.: Alnylam and Regeneron Report Positive Interim Phase 1 Clinical Data on ALN-APP, an Investigational RNAi Therapeutic for Alzheimer's Disease and Cerebral Amyloid Angiopathy

Single Doses of ALN-APP Demonstrated Dose-Dependent, Rapid and Sustained Reduction of sAPPa and sAPPß in Cerebrospinal Fluid, with Up to 90% at Highest Dose to Date Encouraging Clinical Safety and
United States United Kingdom Bryan Crowe Alexandra Bowie Yvonne Greenstreet Pushkal Garg

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