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Regeneron and Alnylam Report Positive Interim Phase 1 Clinical Data on ALN-APP, an Investigational RNAi Therapeutic for Alzheimer's Disease and Cerebral Amyloid Angiopathy

- Single Doses of ALN-APP Demonstrated Dose-Dependent, Rapid and Sustained Reduction of sAPPα and sAPPβ in Cerebrospinal Fluid, with Up to 90% at Highest Dose to Date - - Encouraging... | April 26, 2023
United Kingdom United States Pushkal Garg Alexandra Bowie Christine Regan Lindenboom Yvonne Greenstreet

Alnylam Pharmaceuticals, Inc.: Alnylam and Regeneron Report Positive Interim Phase 1 Clinical Data on ALN-APP, an Investigational RNAi Therapeutic for Alzheimer's Disease and Cerebral Amyloid Angiopathy

Single Doses of ALN-APP Demonstrated Dose-Dependent, Rapid and Sustained Reduction of sAPPa and sAPPß in Cerebrospinal Fluid, with Up to 90% at Highest Dose to Date Encouraging Clinical Safety and
United States United Kingdom Bryan Crowe Alexandra Bowie Yvonne Greenstreet Pushkal Garg

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