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St. Jude's Kids Get Support From Four-Legged Furry Friends

The Paws at Play program at St. Jude Children's Research Hospital plays a very important part in helping families cope with their child's diagnosis. They are trained as service dogs that distract patients from their symptoms, illness, pain, and anxiety. They are there to motivate and support too with social interaction.
United States North Carolina Jude Children Research Hospital Jude Children Research Hospital Dogs That Help
Source: wgna.com

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Turning CAR-T tech against solid tumors by targeting protein fragments in cancer cells

A University of Pennsylvania team has developed a new type of engineered immune cell called “peptide-centric” CAR-T that's designed to shrink solid tumors by targeting proteins inside cancer cells. CAR-T cells developed with the technology eradicated neuroblastoma in mouse models and could move into human trials in 2022 or 2023.
United States John Maris Pete Smith Penn Perelman School Of Medicine University Of Pennsylvania Children Hospital Philadelphia Myrio Therapeutics

Yale spinout shows how targeting cancer cells' acidic environment might enhance immunotherapy

Yale University spinout Cybrexa Therapeutics has developed a peptide-drug conjugate that, instead of aiming for a specific antigen, targets the acidic environment of cancer cells to deliver a toxic payload. The drug improved the efficacy of checkpoint inhibitors in mouse models of cancer.
Yale University United States New Haven Ranjit Bindra Sophia Gayle Daiichi Sankyo Enhertu

Tmunity stops solid tumor CAR-T trial after 2 patients die

Jun 3, 2021 8:40am The setback has led to the winding down of the CART-PSMA-TGFβRDN study. (Image by Dimitris Vetsikas from Pixabay) Tmunity Therapeutics has stopped development of its lead CAR-T therapy after two patients died of a form of neurotoxicity. The news, details of which were first reported by Endpoints, has implications for the broader push to establish cell therapies as treatments for solid tumors. Founded by Carl June, M.D., and Oz Azam, M.D., Tmunity is at the forefron...
Oz Azam University Of Pennsylvania Tmunity Therapeutics Carl June University Of Pennsylvania Carl June

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