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Why leukemic stem cells not harmed by chemotherapy begin to grow and produce AML cells after treatment

Why leukemic stem cells not harmed by chemotherapy begin to grow and produce AML cells after treatment
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

United kingdomOlaf heidenreichSophie kellawaySuzanne rixSophieg kellawayConstanze boniferNewcastle universityUniversity of birminghamGenomic sciencesNature communicationsPrincess maxima centerUniversity of nottinghamInstitute of cancerPediatric oncologyBlood cancer united kingdom

Halting Awakening of Dormant Leukaemia Cells to Prevent Relapse

Halting Awakening of Dormant Leukaemia Cells to Prevent Relapse
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

United kingdomOlaf heidenreichSophie kellawaySuzanne rixConstanze boniferGenomic sciencesInstitute of cancerPrincess maxima centre of pediatricUniversity of birminghamUniversity of nottinghamResearch councilPrincess maxima centre of pediatric oncologyNature communicationsNewcastle universityPrincess maxima centreAcute myeloid leukaemia

Cancer Researchers Reveal How Mutations in a Single Gene Can Cause Different Diseases

Read Time: Leading cancer experts at the University of Birmingham have solved a long-standing question of how various types of mutations in just one gene cause different types of diseases. A team of scientists at the Universityâs Institute of Cancer and Genomic Sciences, led by Professor Constanze Bonifer, studied a gene known as RUNX1, which is responsible for providing instructions for the development of all blood cells and is frequently mutated in blood cancers. The results of their research has shown that the balance of cells types in the blood is affected much earlier than previously thought, which is particularly important for families that carry the mutant gene.

United kingdomSophie kellawayRachel kahnConstanze boniferLife science allianceKay kendall leukaemia fundInstitute of cancerGenomic sciencesResearch communicationsUniversity of birminghamSciences research councilProfessor constanze boniferFamilial platelet disorderAcute myeloid leukaemiaBiological sciences research councilBlood cancer united

Cancer research reveals how mutations in a specific gene cause different types of disease

Credit: University of Birmingham Leading cancer experts at the University of Birmingham have solved a long-standing question of how various types of mutations in just one gene cause different types of diseases. A team of scientists at the University s Institute of Cancer and Genomic Sciences, led by Professor Constanze Bonifer, studied a gene known as RUNX1, which is responsible for providing instructions for the development of all blood cells and is frequently mutated in blood cancers. The results of their research has shown that the balance of cells types in the blood is affected much earlier than previously thought, which is particularly important for families that carry the mutant gene.

United kingdomGemma mckinneySophie kellawayRachel kahnConstanze boniferLife science allianceKay kendall leukaemia fundGenomic sciencesResearch communicationsUniversity of birminghamUniversity institute of cancerSciences research councilProfessor constanze boniferFamilial platelet disorderAcute myeloid leukaemiaBiological sciences research council