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SGLT2 inhibitors reduce cardiovascular events among heart failure patients with mildly reduced and preserved ejection fraction

An analysis of more than 12,000 patients has found that the SGLT2 inhibitors dapagliflozin and empagliflozin reduce cardiovascular death or hospitalization for heart failure by 20% in heart failure patients with mildly reduced and preserved ejection fraction.
United States Muthiah Vaduganathan Emily Henderson York Heart Association Harvard Medical School Hot Line

Restrictive oxygenation target in comatose, post cardiac arrest patients does not cause harm

A restrictive oxygenation target in comatose patients resuscitated after out-of-hospital cardiac arrest does not worsen survival or neurological outcome compared with a liberal target, according to late breaking research presented in a Hot Line session today at ESC Congress 2022.
Jacob Moller Emily Henderson Odense University Hospital Hot Line Study Author Cerebral Performance Category

Sacubitril/valsartan does not change cognitive function in patients with heart failure

Sacubitril/valsartan does not change cognitive function, compared with valsartan, in patients with heart failure and mildly reduced or preserved ejection fraction, according to late breaking research presented in a Hot Line session today at ESC Congress 2022.
United Kingdom John Mcmurray Emily Henderson Drug Administration University Of Glasgow Hot Line

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Gene expression in male and female brains become more similar with age, study says

When male and female fruit flies age, their brains become desexualized. Age-related changes take place in both sexes, but the male brain becomes feminized to a larger extent than the female brain becomes masculinized. This is the conclusion of a study performed by a research group at Linkรถping University. The findings are published in the journal Proceedings of the Royal Society of London B.
City Of United Kingdom Emily Henderson Proceedings Of The Royal Society London University Of Reggio Calabria Department Of Physics

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