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Novartis investigational iptacopan Phase III study demonstrates clinically meaningful and statistically significant proteinuria reduction in patients with C3 glomerulopathy (C3G)

Ad hoc announcement pursuant to Art. 53 LR Phase III APPEAR-C3G study met its primary endpoint, demonstrating superiority of iptacopan vs. placebo in proteinuria reduction at six-month analysis1;...
Czech Republic United States Sloan Simpson Satoshi Sugimoto Parag Mahanti Isabella Zinck

Pharvaris Announces Positive Top-line Phase 2 Data from the CHAPTER-1 Study of Deucrictibant for the Prophylactic Treatment of HAE Attacks

Primary endpoint met: deucrictibant significantly reduced attack rate The primary endpoint of the CHAPTER-1 study measured the time-normalized number of investigator-confirmed HAE attacks during the treatment period. The monthly attack rate was reduced by 84.5% (p=0.0008) compared to placebo in participants who received 40 mg/day of deucrictibant. Primary endpoint met; 40 mg/day orally administered deucrictibant significantly reduced mean monthly attack rate by 84.5% (p=0.0008) compared to place
Berndt Modig Marca Riedl Peng Lu Office Of Pharvaris Us Hereditary Angioedema Association Angioedema Center
Source: yahoo.com

Youth vaping skyrockets as 85% are exposed to e-cig ads, despite global bans

This cross-national study reveals that 85% of young adults across four countries have been exposed to e-cigarette advertising, despite existing regulations. The research also found a significant association between the level of media exposure and the likelihood of e-cigarette use among the youth.
United Kingdom Four Nations South Australia United States World Health Assembly Us National Youth Tobacco

BRIGHTSTAR: Local Consolidative Therapy with Brigatinib in Tyrosine Kinase Inhibitor-Naïve ALK-Rearranged Metastatic NSCLC

Expert oncologist Yasir Elamin, MD, shares data from the BRIGHTSTAR trial and considers how it may inform real-world use of brigatinib in patient with ALK-rearranged metastatic nonโ€“small cell lung cancer.
Yasir Elamin Local Consolidative Therapy Tyrosine Kinase Inhibitor Na Rearranged Metastatic Non Small Cell Lung Cancer Lung Cancer

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Phase 2a Study of HU6, Rivus Pharmaceuticals' Investigational Controlled Metabolic Accelerator, Demonstrates Clinical Benefit in Patients with High Body Mass Index and Nonalcoholic Fatty Liver Disease

/PRNewswire/ -- Rivus Pharmaceuticals Inc., a clinical-stage biopharmaceutical company dedicated to improving cardiometabolic health, today announced...
United States Alana Rockland Mazen Noureddin Prnewswire Rivus Pharmaceuticals Inc Houston Research Institute Rivus Pharmaceuticals

Technological Advancements and Aging Population Fuel Non-Alcoholic Steatohepatitis Clinical Trials M

The Global Non-Alcoholic Steatohepatitis Clinical Trials Market Size will be worth around US$ 2.6 billion in 2022, according to Future Market Insights. However, between 2022 and 2032, the market is likely to develop significantly, with a projected growth rate of 7%, which is higher than the historical increase. With...
United Kingdom United States New York Sagimet Biosciences Gilead Sciences Market Insights Inc

New Clinical and Real-World Data for Genentech's Vabysmo at ASRS Reveal Improved Outcomes for People With Two Leading Causes of Vision Loss

โ€’ Late-breaking post-hoc data indicate Vabysmo leads to less fibrosis, which may negatively impact vision, than aflibercept in people with diabetic macular edema (DME) โ€“โ€’ Real-world data reinforce that first-line Vabysmo use improves outcomes and extends treatment intervals rapidly during the first four months for p...
United States United Kingdom South San Francisco Danielle Haney Adam Pryor Levi Garraway

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