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New Affordable Method for Producing Hindered Amines

At the North Carolina State University, scientists have come up with an affordable and quicker method for generating hindered amines. Hindered amines are a class of chemicals utilized as building blocks in products varying from pharmaceuticals and agrochemicals to organic light-emitting diodes and detergents.
Milad Abolhasani Malek Ibrahim Carolina State University North Carolina State University Affordable Method Producing Hindered
Source: azom.com

Researchers create models to study brain metastases that recapitulate the disease

The spreading of different types of cancer cells to the brain, forming brain metastases, is the main cause of morbidity and mortality associated to cancer. Now, a new study led by Cláudia C. Faria, principal investigator in the group of João Taborda Barata at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and neurosurgeon at the Hospital Santa Maria (HSM, CHULN, Portugal), and published today in the scientific journal Cell Reports Medicine* created a library of models t...
Santa Maria Centro Hospitalar Universit Rita Casc Lobo Antunes Taborda Barata Emily Henderson

Researchers reveal the mechanism of action of century-old BCG vaccine

The century-old Bacille Calmette-Guérin (BCG) vaccine against tuberculosis is one of the world's oldest and most widely used vaccines, used to immunize 100 million newborns every year. Given in countries with endemic TB, it has surprisingly been found to protect newborns and young infants against multiple bacterial and viral infections unrelated to TB. There's even some evidence that it can reduce severity of COVID-19.
United States Guinea Bissau Papua New Guinea Greg Michelotti Joann Diray Arce Bacille Calmette

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Researchers create 3D in vitro model that reveals the origins of human spine

The spinal column is the central supporting structure of the skeleton in all vertebrates. Not only does it provide a place for muscles to attach, it also protects the spinal cord and nerve roots. Defects in its development are known to cause rare hereditary diseases.
Comunidad Autonoma De Cataluna Marina Sanaki Matsumiya Emily Henderson Miki Ebisuya Ebisuya Group Nature Communications

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