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Study reveals connection between oral sex and oropharyngeal cancer A wide breadth of behaviors surrounding oral sex may affect the risk of oral HPV infection and of a virus-associated head and neck cancer that can be spread through this route, a new study led by researchers at the Johns Hopkins Kimmel Cancer Center suggests. These findings add nuance to the connection between oral sex and oropharyngeal cancer -- tumors that occur in the mouth and throat -- and could help inform research and pub...

Researchers discover unexpected role for the clock gene in prostate cancer progression Our biological or circadian clock synchronizes all our bodily processes to the natural rhythms of light and dark. Its no wonder then that disrupting the clock can wreak havoc on our body. In fact, studies have shown that when circadian rhythms are disturbed through sleep deprivation, jet lag, or shift work, there is an increased incidence of some cancers including prostate cancer, which is the second leading ...

New drug reduces tumor volume and pain in patients with neurofibromatosis type 1 Based on preclinical studies of an investigational drug to treat peripheral nerve tumors, researchers at Childrens Hospital of Philadelphia (CHOP) as part of the Neurofibromatosis Clinical Trials Consortium have shown that the drug, cabozantinib, reduces tumor volume and pain in patients with the genetic disorder neurofibromatosis type 1 (NF1). The results of the Phase 2 clinical trial, co-chaired by Michael J. Fis...

In a new study, researchers at Karolinska Institutet in Sweden have used a urine test to identify and verify a patient's type of asthma.

An analysis of a large nationally representative longitudinal study by University of California San Diego Herbert Wertheim School of Public Health and Human Longevity Science report that starting tobacco products, including e-cigarettes, before the age of 18 is a major risk factor for people becoming daily cigarette smokers.

Patients taking immunosuppressive drugs did not have worse COVID-19 outcomes People taking immunosuppressive drugs to prevent organ transplant rejection or to treat inflammatory or autoimmune diseases do not fare worse than others on average when they are hospitalized with COVID-19, according to a study from researchers at the Johns Hopkins Bloomberg School of Public Health. Estimates suggest that there are approximately 10 million immunocompromised people in the U.S. alone. Suppression of the ...

Despite reopening of schools, serious COVID-19 is rare among children Sweden was one of only a few countries that kept preschools, primary and lower secondary schools open during the spring of the pandemic year of 2020. So far, little research has been done on the risk of children being seriously affected by COVID-19 when the schools were open. A study from Karolinska Institutet in Sweden has now shown that one child in 130,000 was treated in an intensive care unit on account of COVID-19 during...

Mass spectrometry imaging shows promise in diagnosing brain diseases Medical professionals all want to be able to quickly and correctly diagnose diseases. Their future ability to do so will depend on identifying what biochemicals are present in tissue sections, where the biomolecules are, and at what concentrations. For this purpose, mass spectrometry imaging—which can identify multiple biochemicals in a single experiment—will be useful. However, the stability of biomolecular sampling needs...

New Nanoparticle Platform Could Help Treat Various Neurological Disorders Written by AZoNanoJan 4 2021 Over the last few decades, scientists have established the biological pathways that cause neurodegenerative diseases and have created potential molecular agents to target these pathways. Yet, there has been a delay in translating these discoveries into clinically approved treatments, partially due to the challenges faced by researchers in delivering therapeutics into the brain through the bloo...

Study reveals how ecDNA fragments drive gene amplification to generate drug resistance in cancer Researchers led by Ludwig San Diego Member Don Cleveland and Peter Campbell of the Sanger Center have solved the mystery of how free-floating circular DNA fragments, which are almost exclusively found in cancer cells, drive gene amplification to generate drug resistance in cancer. The research, published on December 23 in the journal Nature, provides new insights into how cancers evolve to adapt to...