Gaining a better understanding of and improving outcomes for sepsis are the focus
of Flavia Machado s career. Speaking to The Lancet Respiratory Medicine in her office
in São Paulo Hospital (São Paulo, Brazil) she explains, “It is absolutely critical
that all health-care workers understand that the patient they have in front of them
could have sepsis, and in most cases there is a critical 1 h window for starting antibiotic
therapy. We must also continue to educate the public about this killer condition.”
Evaluating risk stratification and sepsis-related mortality in patients with positive blood cultures via procalcitonin combined with the PIRO system in the ED.
Shock causes significant morbidity and mortality in children living in resource-limited settings. Simulation has been successfully used as an educational tool for medical professionals internationally. We sought to improve comfort and knowledge regarding shock recognition and fluid management by implementing a pediatric shock curriculum using simulation as an assessment for trainees in Manila, Philippines. We assessed a shock curriculum focused on patients with malnutrition in a prospective cohort study, using a written test and a videotaped simulation-based objective standardized clinical examination. Implementation occurred in March 2020 with 24 Filipino pediatric residents at a single institution in Manila. Outcomes included time to initiation of fluid resuscitation, improvement in confidence, knowledge on a written assessment, and performance in simulation. Results were compared pre- and post-intervention using Wilcoxon signed-rank test. The time to initiation of fluids did not cha
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