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IMAGE: Pathway of mutant p53 from liquid droplets to gel-like and solid-like (amyloid) states, in vitro and in cell. view more
Credit: Guilherme de Oliveira
Cancer has been recently shown to be affected by protein clusters, particularly by the aggregation of mutant variants of the tumor suppressor protein p53, which are present in more than half of malignant tumors. However, how the aggregates are formed is not yet fully understood. The understanding of this process is expected to provide new therapeutic tools able to prevent proteins to clump and cancer progression.
In Brazil, researchers at the Federal University of Rio de Janeiro have identified a key mechanism behind the mutant p53 aggregation process, linked to cancer pathology, opening new paths for the development of novels drugs against the disease.
Article Title: Investigation of SARS-CoV-2 infection in dogs and cats of humans diagnosed with COVID-19 in Rio de Janeiro, Brazil
Funding: MMS: This study was supported by CGLab/MoH (General Laboratories Coordination of Brazilian Ministry of Health), CVSLR/FIOCRUZ (Coordination of Health Surveillance and Reference Laboratories of Oswaldo Cruz Foundation), The National Council for Scientific and Technological Development (CNPq) COVID-19 MCTI 402457/2020-0, INOVA VPPCB-005-FIO-20-2-69, and Carlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro (FAPERJ) E26/210.196/2020.
Competing Interests: The authors have declared that no competing interests exist.
Recently, a published study in Science Advances assessed the contribution of pollinators to international market flows and showed that biodiversity conservation
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Energy Daily News
2021 JAN 26 (NewsRx) By a News Reporter-Staff News Editor at Energy Daily News A new study on Energy - Electric Power is now available. According to news reporting originating from Londrina, Brazil, by NewsRx correspondents, research stated, “Smart Grid (SG) is a multidisciplinary concept related to the power system update and improvement. SG implies real-time information with specific communication requirements.”
Financial supporters for this research include CAPES, National Council for Scientific and Technological Development (CNPq), State University of Londrina -Paran State Government (UEL).
Our news editors obtained a quote from the research from State University Londrina, “System reliability relies on the best capabilities for monitoring and controlling the grid. Among other aspects, SG applications involve three main challenges, sufficient real-time capable measurement units, managing large data sets, and two-way low-latency communicati
Deeper insight into how tick spit suppresses cattle immunity
- A tick saliva study reveals immune responses that could lead to better protection for cattle
- This is a joint press release by Hokkaido University, Japan; Universidade Federal do Rio Grande do Sul, Brazil; and Universidade Federal do Rio de Janeiro, Brazil
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SAPPORO, Japan, Jan. 28, 2021 /PRNewswire/ Scientists from Hokkaido University, Japan and Universidade Federal do Rio Grande do Sul and Universidade Federal do Rio de Janeiro, Brazil, have revealed that substances in tick saliva activates immune response-suppressing proteins in cattle that facilitates the transmission of tick-borne diseases. The finding was published in the journal