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Europe approves KEYTRUDA as first-line colorectal cancer therapy

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France General United Kingdom Northern Ireland Great Britain Thierry Andre Sorbonne University

Merck & Co., Inc.: European Commission Approves KEYTRUDA (pembrolizumab) as First-Line Treatment in Adult Patients With Metastatic Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Colorectal Cancer

(2) KEYTRUDA Is First Checkpoint Inhibitor Approved in Europe to Treat MSI-H or dMMR Colorectal Cancer European Approval Based on Results From KEYNOTE-177 Trial Demonstrating KEYTRUDA Significantly Reduced Risk of Disease Progression or Death by 40% Compared With Chemotherapy Merck (NYSE: MRK), known as MSD outside the United States and Canada, announced today that the European Commission has approved KEYTRUDA, Mercks anti-PD-1 therapy, as a monotherapy for the first-line treatment of adult pa...
United States France General United Kingdom Northern Ireland Great Britain Scot Ebbinghaus

New Anti-PD-1 Drug Active in Advanced Colon Cancer

This article is a collaboration between MedPage Today and: Almost 40% of progressive, advanced gastrointestinal (GI) tumors with mismatch repair deficiency (dMMR) responded to the investigational anti-PD-1 agent dostarlimab, according to a preliminary clinical trial. Overall, 38.7% of 106 patients responded to single-agent treatment with monoclonal antibody, including 36.2% of colorectal cancers (CRC) and 43.2% of all other tumors, which were primarily GI in origin. About three-fourths of pati...
France General Charles Bankhead Thierry Andre John Krauss University Of Michigan Medical Center Sorbonne University

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