Third Universal Definition News Today

The rate of major AEs was fourfold higher with surgery, yet deaths were higher post-PCI, rekindling old debates.

December 11, 2020 A new analysis of the ISCHEMIA trial reveals its results are highly contingent on how myocardial infarction is defined, with investigators reporting a significant treatment difference between the invasive and conservative strategies when counting MIs using the more-sensitive biomarker: cardiac troponin (cTn). When investigators analyzed events based on the secondary MI definition, which assessed PCI- and CABG-related infarctions using cTn levels as opposed to CK-MB, the conser...