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TEPEZZA® (teprotumumab) Approved in Brazil for the Treatment of Active Thyroid Eye Disease (TED) - Horizon Therapeutics (NASDAQ:HZNP)

-- First and only medicine approved in Brazil for the treatment of active TED, a serious, progressive, debilitating and potentially vision-threatening rare autoimmune disease -- Horizon Therapeutics plc (NASDAQ:HZNP)
United States Vikram Karnani European Group On Grave Orbitopathy European Group On Grave Brazilian Health Regulatory Agency Drug Administration

Horizon Therapeutics plc Announces Positive Topline Data from Phase 3 Clinical Trial (OPTIC-J) in Japan Evaluating TEPEZZA® (teprotumumab-trbw) for the Treatment of Active Thyroid Eye Disease (TED)

-- At Week 24, 89% of patients treated with TEPEZZA had a clinically meaningful improvement in proptosis (≥2 mm) compared with 11% of patients receiving placebo --
United States Yuji Hiromatsu Japan Pharmaceuticals Kurume University Medical Center European Group On Grave Orbitopathy Exchange Commission

New Data from TEPEZZA® (teprotumumab-trbw) Clinical Trials and Real-World Analyses Shed Light on Link Between Thyroid Autoimmunity and Hearing Risks

Horizon Therapeutics plc today announced the presentation of a series of analyses demonstrating the risk of hearing-related events among people with Graves’ disease and TED, including among... | June 17, 2023
United States Terry Smith Jeffreyw Sherman European Group On Grave Orbitopathy Wk Kellogg Eye Center Endocrine Society Annual Meeting

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Additional Data from Phase 4 TEPEZZA® (teprotumumab-trbw) Clinical Trial Presented at the Endocrine Society Annual Meeting Reinforces Efficacy in People with Thyroid Eye Disease (TED) Regardless of Disease Activity or Duration

-- Data at Week 24 show 2.41 mm reduction in proptosis in patients treated with TEPEZZA compared with 0.92 mm in those who received placebo; 62% of TEPEZZA patients had clinically meaningful... | June 17, 2023
United States Raymond Douglas Los Angeles Beth Scott Drug Administration Endocrine Society Annual Meeting

Horizon Therapeutics plc Announces Data from the TEPEZZA® (teprotumumab-trbw) Phase 4 Clinical Trial in Patients with Chronic/Low CAS Thyroid Eye Disease (TED) to be Presented at the Upcoming Endocrine Society (ENDO) Annual Meeting

-- TEPEZZA Phase 4 trial results to be shared in an oral presentation on Saturday, June 17 at 3:30 p.m. CT -- -- Two patients will share their real-world experience living with TED and being... | June 5, 2023
Olmsted County United States Jeffreyw Sherman Malini Gupta Duke University Health System European Group On Grave Orbitopathy

Horizon Therapeutics plc Announces Initiation of Phase 3 Clinical Trial in Japan Evaluating TEPEZZA® (teprotumumab-trbw) in Adults with Chronic/Low Clinical Activity Score (CAS) Thyroid Eye Disease (TED)

Horizon Therapeutics plc today announced that the first patient has been enrolled in a Phase 3 clinical trial in Japan evaluating TEPEZZA for the treatment of adults with chronic Thyroid Eye Disease... | May 1, 2023
United States Elizabethhz Thompson Drug Administration Devices Agency Japan Pharmaceuticals European Group On Grave Orbitopathy

Horizon Therapeutics plc Announces Initiation of Phase 3 Clinical Trial in Japan Evaluating TEPEZZA®

DUBLIN--(BUSINESS WIRE)--Horizon Therapeutics plc (Nasdaq: HZNP) today announced that the first patient has been enrolled in a Phase 3 clinical trial in Japan evaluating TEPEZZA for the treatment of adults with chronic Thyroid Eye Disease (TED) and low clinical activity score (CAS), which is a measure of disease act...
United States Erin Linnihan Elizabethhz Thompson Tina Ventura Maggie Fairchild Rachel Vann

Horizon Therapeutics plc Announces FDA Approval of an Update to the Indication Language for TEPEZZA (teprotumumab-trbw) to Specify its Use in Thyroid Eye Disease (TED) Patients Regardless of Disease Activity or Duration

-- Updated indication language reinforces the importance of unrestricted access for patients across full spectrum of Thyroid Eye Disease -- Horizon Therapeutics plc (Nasdaq: HZNP) today announced
United States Tina Ventura Rachel Vann Tim Walbert European Group On Grave Orbitopathy Exchange Commission

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