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Exhibit 4.10.1 First Amendment to Amended and Restated Credit Agreement and Guaranty This First Amendment. | June 18, 2023

United statesState of new yorkNew yorkAris kekedjianRonan ocaoimhJohn gillardSam chawlaTrinity biotech manufacturingDiagnostics incTrinity biotech incPerceptive credit opportunitiesTrinity researchTrinity biotechNova century scientific incTrinity biotech joint ventureBiosynth international inc