Typei Interferon News Today

This article explores the role of type I interferon and CD8+ T cell detection in predicting rectaladenocarcinoma.

The study published in Nature Cardiovascular Research reveals that SARS-CoV-2, the virus causing COVID-19, can directly infect coronary vessels and arterial plaques, heightening the risk of cardiovascular complications like heart attacks and strokes. These findings offer critical insights into the increased long-term cardiovascular risks for COVID-19 survivors and open new avenues for targeted therapies.

A recent review in the journal Immunity delves into the crucial role of dendritic cells (DCs) in shaping T-cell responses in cancer, highlighting their importance in both priming anti-tumor immunity and in ongoing immune interactions within tumors. The findings underscore the potential of DCs as key targets for next-generation cancer immunotherapies.

A research team from the LKS Faculty of Medicine at HKUMed has identified an unexpected driver of cancer immunotherapy resistance. 

A research team from the LKS Faculty of Medicine, the University of Hong Kong (HKUMed) has identified an unexpected driver of cancer immunotherapy resistance: the harmful effect of chronic Type I Interferon signaling on tumor-killing CD8+ T cells.

We speak with postdoctoral researcher Erola Pairo-Castineira about her recent work which aimed to find the genetic factors that may predispose individuals to critical COVID-19 and learn how COVID-19 affects cells in the body.

What is going on at the single-cell level in the first days of SARS-CoV-2 infection in the lungs?

SAN ANTONIO (February 8, 2022) – What is going on at the single-cell level in the first days of SARS-CoV-2 infection in the lungs? Researchers at

Strategies include narrow-front and broad-front attacks—for both, the necessary armaments are in the works.

Dengue virus infection is prevalent in tropical and sub-tropical regions of the world, which is fatal if untreated symptomatically. Emergence of new genotype within serotypes led to enhanced severity. The objective of the study is to identify the molecular characteristics of the DENV circulated during 2017 outbreak in Tamil Nadu, India and, to investigate the role of inflammatory cytokines in different ‘serotypes’ and in ‘dengue severity’. A total of 135 suspected samples were tested for...