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NSW spearheads key COVID-19 vaccine research
A leading group of NSW experts will pioneer Australia-first research to inform vaccine policy in the state and beyond.
The Vaccine, Infection and Immunology (VIIM) Collaborative Research Group will receive more than $4.5 million in funding from the NSW Government over three years to study the clinical and immunological responses to COVID-19 vaccines in NSW recipients.
VIIM brings together the leading vaccine, infection and immunology researchers and practitioners in NSW. It incorporates expertise from two universities, four medical research institutes, the state-wide pathology service, adult and paediatric health services, and the National Centre for Immunisation Research and Surveillance.
Because NSW has not been heavily exposed to the virus, the state is in a unique opportunity to study COVID-19 vaccines, taking on the “trickiest questions”, such as how it compares with immunity from infection and whether boosters are needed.
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The early immune response in a person who has been vaccinated for COVID-19 can predict the level of protection they will have to the virus over time, according to analysis from Australian mathematicians, clinicians, and scientists, and published the journal Nature Medicine. The researchers from the University of New South Wales s Kirby Institute, the Peter Doherty Institute for Infection and Immunity, and the University of Sydney have identified an immune correlate of vaccine protection. This has the potential to dramatically cut development times for new vaccines, by measuring neutralising antibody levels as a proxy for immune protection from COVID-19. Neutralising antibodies are tiny Y-shaped proteins produced by our body in response to infection or vaccination. They bind to the virus, reducing its ability to infect, says Dr Deborah Cromer from the Kirby Institute.