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 E-Mail IMAGE: Image of cilia in a mouse brain using Scanning Electron Microscopy, imaged and processed by Calvin S. Carter. view more  Credit: Calvin S. Carter Mice with symptoms that mimic Bardet-Biedl Syndrome (BBS) have difficulty with learning and generating new neurons in the hippocampus. However, according to a new study by Thomas Pak, Calvin Carter, and Val Sheffield of the University of Iowa, published April 22nd in the journal PLOS Genetics, these mental defects can be successfully treated with lithium. BBS is a rare genetic disorder that causes intellectual disability, vision loss and obesity, and sometimes kidney problems and extra fingers and toes. It is one of several ciliopathies, which are diseases that stem from defective cilia tiny, finger-like projections on the surface of cells that play important roles in moving fluids, sensing the environment and signaling between cells. Pak, Carter, Sheffield and colleagues wanted to learn more about how ciliop

United statesCalvin carterThomas pakLouis stokes va medical centerAmerican heart associationBrockman foundationNational institute of healthAllen initiative in brain healthUniversity of iowaRoyj carver charitableBardet biedl syndromeVal sheffieldNational instituteCharitable trustLouis stokesAmerican heart association allen initiative