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Frontiers | Exploiting hiPSCs in Leber's Hereditary Optic Neuropathy (LHON): Present Achievements and Future Perspectives

More than thirty years after discovering Leberโ€™s hereditary optic neuropathy (LHON) as the first maternally inherited disease associated with homoplasmic mtDNA mutations, we still struggle to achieve effective therapies. LHON is characterized by selective degeneration of retinal ganglion cells (RGCs) and is the most frequent mitochondrial disease, which leads to blindness young people, in particular males. Despite the causative mutations are present in all tissues, yet only a specific cell typ...
South Korea Trentino Alto Adige Friuli Venezia Giulia Ch Ungch Ong Namdo Doug Wallace Istituto Neurologico Carlo Besta

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Report Focuses On Protecting Kids With Disabilities From Sexual Abuse

According to the U.S. Bureau of Justice Statistics, people with intellectual or developmental disabilities are seven times more likely to be sexually assaulted or raped โ€” and the likelihood is 12 times greater for females. Melissa Van Hook chairs the Arizona Developmental Disabilities Planning Council. During a Zoom call with educators, she talked about the challenges facing these families. "What was discovered was that individuals and families are not receiving the information they needed to...
United States Arizona Developmental Disabilities Planning Council Us Bureau Of Justice Statistics Justice Statistics Van Hook Arizona Developmental Disabilities Planning
Source: kjzz.org

Hospital cyberattacks delay patient care, affect safety

Getty Images Last Tuesday, Jason Cabot prepped for an abdominal surgery: he fasted for 24 hours and drank three tablespoons of intestine-cleansing milk of magnesia. But until he showed up at 5:30 a.m. the next day at Scripps Mercy Health in San Diego, he had no idea if the surgery was going to happen. Scripps Health, a large health system in California, on May 1 experienced a "disruption" to its IT systems, which has since been tied to malware discovered on the health systems computer network....
United States San Diego Palo Alto Eric Johnson Christoph Lehmann Valerie Montague

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