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Scientists Improve Anti-Tumor Power of CAR-T Cells

Scientists Improve Anti-Tumor Power of CAR-T Cells
insideprecisionmedicine.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from insideprecisionmedicine.com Daily Mail and Mail on Sunday newspapers.

Switzerland generalAlison jaccardMathias wenesGeneva university hospitalsDepartment of medicineVaud university hospitalDepartment of oncology

Strengthening artificial immune cells to figh

Among available immunotherapies, the use of «CAR-T» cells is proving extremely effective against certain blood cancers, but only in half of patients. A main reason for this is the premature dysfunction of these immune cells, which have been artificially modified in vitro. A team from the Universities of Geneva (UNIGE), Lausanne (UNIL), the Geneva University Hospitals (HUG) and the Vaud University Hospital (CHUV), all part of the Swiss Cancer Center Léman (SCCL), has discovered how to prolong the functionality of CAR-T cells. By inhibiting a very specific metabolic mechanism, the team has succeeded in creating CAR-T cells with enhanced immune memory, capable of fighting tumour cells for much longer. These are very promising results, to be read in the journal Nature.

Switzerland generalMathias wenesDenis miglioriniAlison jaccardVaud university hospitalGeneva university hospitalsMethod of researchSwiss cancer centerDepartment of oncologyDepartment of medicine

Creating CAR-T cells with enhanced immune memory to fight cancer

Among available immunotherapies, the use of «CAR-T» cells is proving extremely effective against certain blood cancers, but only in half of patients.

Switzerland generalDenis miglioriniAlison jaccardMathias wenesDanielle ellisDepartment of medicineGeneva university hospitalsVaud university hospitalDepartment of oncologySwiss cancer centerN vitro

Strengthening artificial immune cells to fight cancer

Strengthening artificial immune cells to fight cancer
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

Switzerland generalDenis miglioriniMathias wenesAlison jaccardDepartment of oncologyGeneva university hospitalsDepartment of medicineVaud university hospitalSwiss cancer centerNature september

Strengthening artificial immune cells to figh

Among available immunotherapies, the use of «CAR-T» cells is proving extremely effective against certain blood cancers, but only in half of patients. A main reason for this is the premature dysfunction of these immune cells, which have been artificially modified in vitro. A team from the Universities of Geneva (UNIGE), Lausanne (UNIL), the Geneva University Hospitals (HUG) and the Vaud University Hospital (CHUV), all part of the Swiss Cancer Center Léman (SCCL), has discovered how to prolong the functionality of CAR-T cells. By inhibiting a very specific metabolic mechanism, the team has succeeded in creating CAR-T cells with enhanced immune memory, capable of fighting tumour cells for much longer. These are very promising results, to be read in the journal Nature.

Switzerland generalMathias wenesAlison jaccardDenis miglioriniVaud university hospitalDepartment of medicineSwiss cancer centerGeneva university hospitalsDepartment of oncologyMethod of research