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Researchers concluded that PTSD, TBI, and a specific variant of the APOE gene showed strong associations with Alzheimer disease and related dementias (ADRD).

Head injury and post-traumatic stress disorder, or PTSD, may increase the risk of developing Alzheimer's disease among people who carry a certain genetic variant, a study of U.S. military veterans suggests.

The influence of post-traumatic stress disorder (PTSD), traumatic brain injury (TBI), and genetic risk factors in a large cohort have never been studied simultaneously in the medical community.

The medical community has never researched the simultaneous impact of post-traumatic stress disorder (PTSD), traumatic brain injury (TBI), and genetic risk factors in a large cohort … until now.

In the largest-ever genetic study of dementia in people of African ancestry, VA researchers identified several genetic risks different from those seen in people of European ancestry.

That means study results using only one ethnic group may not apply to other groups, hindering dementia prevention and treatment, the study said.For example, studies have found that a gene variant called APOE E4 carries the largest genetic risk for Alzheimers disease in people with European ancestry, but the effect of APOE E4 is half as strong in people of African ancestry, the study said.Increasing the representation of non-European ancestry populations in genome-wide association studies has bee...

Get latest articles and stories on Science at LatestLY. According to a research published in the journal Molecular Psychiatry, scientists discovered many instances where gene variations may increase the risk of Alzheimers disease and related dementias among people of African ancestry. Science News | Study Reveals Genetic Risk for Dementia Among People of African Descent.

Researchers discovered many genetic risks distinct from those seen in people of European descent in the largest-ever genomic investigation of dementia in people

The impact of traumatic brain injury (TBI), post-traumatic stress disorder (PTSD), and genetic risk factors in a large cohort has never previously been studied

Researchers discovered many genetic risks distinct from those seen in people of European descent in the largest-ever genomic investigation of dementia in people