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Gene Dyrk1a Linked to Heart Defects in Down Syndrome Identified

In Down syndrome patients, partially mitigating the overactivity of the Dyrk1a gene in mice reversed the defects laying the groundwork for potential future therapies.

Rifdat aoidiVictor tybulewiczEva lana elolaPrincipal laboratory research scientistPostdoctoral project research scientistScience translational medicineMissing linkDown syndrome heart defectsGroup leaderImmune cell biology laboratoryDown syndrome laboratoryDown syndromeHeart defectsBirth defects

Gene behind Down syndrome heart defects identified

Gene behind Down syndrome heart defects identified
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Eva lana elolaVictor tybulewiczPrincipal laboratory research scientistFrancis crick instituteUniversity college londonPerha pharmaceuticalsQueen square institute of neurologyFrancis crickUniversity collegeProfessor elizabeth fisherSquare instituteScience translational medicineTube widget placeholderGroup leaderImmune cell biology laboratoryDown syndrome laboratory

Overactive Gene Linked to Heart Defects in Down Syndrome

Overactive Gene Linked to Heart Defects in Down Syndrome
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Rifdat aoidiVictor tybulewiczUniversity college londonCell biology laboratory down syndromeFrancis crick institutePerha pharmaceuticalsScience translational medicineImmune cell biology laboratoryDown syndrome laboratory

Gene behind heart defects in Down syndrome identified

Gene behind heart defects in Down syndrome identified

United kingdomCity ofEva lana elolaRifdat aoidiVictor tybulewiczCancer research united kingdomUniversity college londonTimes university of the yearPostdoctoral project research scientistPerha pharmaceuticalsFrancis crick instituteLondon global universityPrincipal laboratory research scientistResearch councilKing college londonImperial college london

Gene behind heart defects in Down syndrome identified

Gene behind heart defects in Down syndrome identified
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Elizabeth fisherVictor tybulewiczRifdat aoidiEva lana elolaFrancis crick instituteScience translational medicineGroup leaderImmune cell biology laboratoryDown syndrome laboratory