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As this may increase your risk of stroke. eliquis can cause serious and in rare cases fatal bleeding. dont take eliquis if you have an artificial heart valve or abnormal bleeding. while taking, you may bruise more easily... or take longer for bleeding to stop. get help right away for unexpected bleeding, or unusual bruising. it may increase your bleeding risk if you take certain medicines. tell your doctor about all planned medical or dental procedures. the number one cardiologist-prescribed blo...