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Patients with type 2 diabetes who were treated with metformin had a 30% reduction in risk for total knee and total hip replacement, compared with patients who did not receive the drug.

Boston universityUnited statesBaylor college of medicineDavidt felsonMenzies institute for medical researchNational natural science foundation of chinaUniversity of tasmaniaTaiwan national health insurance research databaseCanadian medical association journalWu jieping medical foundation programResearch foundationTechnology programChanghai dingMenzies instituteMedical researchCanadian medical association