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CHOP researchers engineer stable, universal MHC-I molecules in a shorter timeframe

Class I major histocompatibility complex (MHC-I) proteins play an essential role in the immune system of all jawed vertebrates. The MHC-I displays peptide fragments of proteins from within the cell on the cell surface, "presenting" them to the immune system, which is constantly scanning the body for foreign or toxic antigens.

CHOP researchers develop universal MHC molecu

Researchers from Children’s Hospital of Philadelphia (CHOP) have engineered stable, universal MHC-I molecules that can be produced rapidly at scale, allowing researchers not only to develop vaccines and immunotherapies more quickly but also to identify molecules that can work broadly across the population. The findings were published today in the Proceedings of the National Academy of Sciences.

CHOP Researchers Develop Universal MHC Molecules that Can be Produced Rapidly at Scale

Researchers Create Universal MHC Molecules for Stable Scalable Use

Researchers develop universal MHC molecules that can be produced rapidly at scale

Class I major histocompatibility complex (MHC-I) proteins play an essential role in the immune system of all jawed vertebrates. The MHC-I displays peptide fragments of proteins from within the cell on the cell surface, "presenting" them to the immune system, which is constantly scanning the body for foreign or toxic antigens.

CHOP Researchers Develop Universal MHC Molecules that Can be Produced Rapidly at Scale

/PRNewswire/ -- Class I major histocompatibility complex (MHC-I) proteins play an essential role in the immune system of all jawed vertebrates. The MHC-I...

CHOP Researchers Develop Universal MHC Molecules that Can be Produced Rapidly at Scale

--The molecules open the door for development of immunotherapies that are truly universal and work across HLA types, regardless of patient ancestr...

3D-printed walls added to wooden home to create Traditional House of the Future

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