Arthritis National Research Foundation Announces 2022-23 Grant Recipients
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Rogue antibodies make cells sticky to trigger blood clots in COVID-19 patients
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Novel autoantibody sparks inflammation, blood clots in Covid patients
Wed, Jul 21 2021 10:21:22 AM
New York, Jul 21 (IANS): US researchers have discovered a functional autoantibody in Covid-19 patients that contributes to the disease s development and the firestorm of blood clots and inflammation it induces.
A growing body of studies suggests Covid-19 emulates many aspects of systemic autoimmune disorders, including the release of a flurry of overactive immune cells that produce toxic webs of proteins and DNA called neutrophil extracellular traps, or NETs.
For this study, the team analysed serum from over 300 hospitalised Covid patients, searching for a novel autoantibody that shields the toxic NETs from being destroyed and produces a lasting noxious effect in a patient s body.
Functional autoantibody in COVID-19 contributes to the firestorm of blood clots and inflammation
Researchers at Michigan Medicine have discovered yet another functional autoantibody in COVID-19 patients that contributes to the disease s development and the firestorm of blood clots and inflammation it induces.
A growing body of studies suggests COVID-19 emulates many aspects of systemic autoimmune disorders, including the release of a flurry of overactive immune cells that produce toxic webs of proteins and DNA called neutrophil extracellular traps, or NETs.
For this study, the team analyzed serum from over 300 hospitalized COVID patients, searching for a novel autoantibody that shields the toxic NETs from being destroyed and produces a lasting noxious effect in a patient s body.