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Highly efficient photodynamic-immunotherapy by combining AIEgen with Poly(I:C)

Credit: ยฉScience China Press Immunotherapy is a type of anti-tumor treatment and has shown great clinical success against a wide variety of malignancies in recent years. Poly(I : C), a TLR3 agonist, is the most potent type I interferon (IFN) inducer. Poly(I : C) not only directly induces tumorous apoptosis, but also stimulates tumor cells to secrete immune factors. However, the immune response rate induced by Poly(I : C) remains low in several types of malignancies and higher doses are often r...
Shixuan Wang Huazhong University Of Science China University Of Geosciences Technology Of China Huazhong University Fan Xia

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