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Formulary Switch From Ibrutinib to Zanubrutinib Yields Positive Safety, Efficacy Data

A real-world report showed the safety and efficacy of zanubrutinib after a community oncology practice replaced ibrutinib with the newer Bruton tyrosine kinase inhibitor on its formulary.

United statesZanubrutinib brukinsaAmerican society of clinical oncologyAmerican societyClinical oncologyKaiser permanente northern californiaImage credit

FDA grants accelerated approval to Brukinsa for advanced follicular lymphoma

FDA grants accelerated approval to Brukinsa for advanced follicular lymphoma
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Zanubrutinib brukinsaMindy valcarcelBymatthew shinkle

Advancing Treatment Selection in CLL Management

Treatment options are distinct in their mechanisms, safety profiles, and implications for patients’ quality of life.

United statesUnited kingdomEli lillyZanubrutinib brukinsaPirtobrutinib jaypircaInternational workshop on chronic lymphocytic leukemiaAlliance for clinical trials in oncologyLilly united statesGenentech incAstrazeneca pharmaceuticalsBeigene ltdExcella gmbh coAbbvie incAmerican society of clinical oncology annual meetingInternational workshopChronic lymphocytic leukemia

From Axatilimab to Zanubrutinib: Treatment Updates Abound

Presentations detail clinical trial results and focus on drugs in the pipeline.

United statesSan diegoMdss mpnsFrellickm zanubrutinibEhlersj tuspetinibSmithj valemetostatRoche columviSyndax incyteTallenta nivolumabEhlersj fedratinibRddady ibrutinibGenentech columviTuspetinib aptose biosciencesIngrami meninRddady daratumumabTallenta isatuximab

Zanubrutinib Showcases Sustained PFS Benefit Vs Ibrutinib in R/R CLL/SLL

Zanubrutinib continued to demonstrate improved progression-free survival benefit over ibrutinib in the treatment of patients with relapsed/refractory chronic lymphocytic leukemia and small lymphocytic lymphoma, according to extended follow-up data from the phase 3 ALPINE trial.

United statesDana farber cancer instituteZanubrutinib brukinsaJenniferr brownHematologic malignanciesMargaret collette professorHematologic oncologyHarvard medical schoolChronic lymphocytic leukemiaSmall lymphocytic leukemiaPhase 3 alpine trialAsh annual meeting