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TO PROXY STATEMENT FOR THE SPECIAL MEETING OF STOCKHOLDERS To be held on November 8, 2023 October 30, 2023 Explanatory Note .

United statesWilliam blairMatthew jonesNeilf mcfarlaneJerry beaveeKevin turnerZevra therapeutics incConcert pharmaceuticals incAmarin corporationIntercept pharmaceuticals incZevra selected public companies analysisSupernus pharmaceuticalsAspenz merger sub incUltragenyx pharmaceuticalsAcer therapeutics incLexicon pharmaceuticals inc