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IMAGE: The researchers customized this adaptive optics scanning light ophthalmoscope to improve the imaging resolution by strategically blocking light in various locations of the instrument. Using less light is an advantage. view more
Credit: Johnny Tam, National Eye Institute
WASHINGTON Researchers have developed a noninvasive technique that can capture images of rod and cone photoreceptors with unprecedented detail. The advance could lead to new treatments and earlier detection for retinal diseases such as macular degeneration, a leading cause of vision loss. We are hopeful that this technique will better reveal subtle changes in the size, shape and distribution of rod and cone photoreceptors in diseases that affect the retina, said research team leader Johnny Tam from the National Eye Institute. Figuring out what happens to these cells before they are lost is an important step toward developing earlier interventions to treat and prevent blindness.
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IMAGE: The mosaic of cone and rod photoreceptor cells is shown by confocal imaging (left) and split detection. view more
Credit: Johnny Tam, Ph.D., National Eye Institute
A team led by scientists at the National Eye Institute (NEI) has noninvasively visualized the light-sensing cells in the back of the eye, known as photoreceptors, in greater detail than ever before. Published in
Optica, the researchers report how they improved imaging resolution by a third by selectively blocking the light used to image the eye. NEI is part of the National Institutes of Health.
The achievement is the latest in an evolving strategy to monitor cell changes in retinal tissue that, in turn, will help identify new ways to treat and prevent vision loss from diseases such as age-related macular degeneration, a leading cause of blindness in people age 65 and older.
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Research from Queen Mary University of London has concluded that there is convincing evidence that type 2 diabetes is associated with an increased risk of Parkinson s disease. The same study found that there was also evidence that type 2 diabetes may contribute to faster disease progression in patients who already have Parkinson s.
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Bottom Line: Cancer survivors had a greater risk of reduced ambulatory function, which was associated with an increased risk of death.
Journal in Which the Study was Published:
Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research
Author: Elizabeth Salerno, PhD, MPH, assistant professor of surgery at Washington University School of Medicine in St. Louis, who conducted the research at the National Cancer Institute
Background: The diagnosis and treatment of cancer has been shown to be associated with poor functional health for common cancer types, such as those of the breast and prostate, but less is known about the association for other cancers, explained Salerno. Given that cancer survivors are living longer than ever, understanding how the diagnosis and treatment of a broad range of cancers may affect ambulatory function a potentially modifiable risk factor could lead to new treatment and rehabilitation strategies to i