Genetic Tools Detect Culprit for Type 1 Diabetes by Angela Mohan on May 21, 2021 at 10:28 AM
Nature.
Type 1 diabetes is am autoimmune disease with loss of insulin-producing pancreatic beta cells. It is less common than type 2 diabetes, but its prevalence is growing. Currently, there is no cure, only disease management.
The U.S. Centers for Disease Control and Prevention projects 5 million Americans will have type 1 diabetes by 2050.
Numerous genome-wide association studies (GWAS) have been conducted in recent years in which researchers compare whole genomes of persons with the same disease or condition, searching for differences in the genetic code that may be associated with that disease or condition.
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The human body is constantly exposed to various environmental actors, from viruses to bacteria to fungi, but most of these microbial organisms provoke little or no response from our skin, which is charged with monitoring and protecting from external dangers.
Until now, researchers weren t quite sure how that happened and why our skin wasn t constantly alarmed and inflamed.
In a study published May 21, 2021 in
Science Immunology, scientists at University of California San Diego School of Medicine identify and describe two enzymes responsible for protecting our skin and body s overall health from countless potential microbial intruders. These enzymes, called histone deacetylases (HDACs), inhibit the body s inflammatory response in the skin.
Investigators map how drugs were used on people hospitalized with COVID-19 infection
A record of medicine utilization patterns assembled by an interdisciplinary team of researchers at the University of California, Irvine and the UC San Diego School of Medicine reveals the thought, care and scientific rigor clinicians at UC Health medical centers applied in their treatment of patients with COVID-19 in 2020.
For a study published today in
Journal of the American Medical Association Network Open, the investigators examined data on the usage rates of 10 different medicines and medicine categories to map how drugs were used on people hospitalized with the viral infection.
Efforts to treat COVID-19 patients chronicled in UC Health medications data eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.
Clinical trial looks at cannabis as a potentially effective treatment for acute migraines
Allison Knigge was in elementary school when she started to experience migraines. They continued to get progressively worse as time went on, especially after the birth of her son. I would describe my migraines as a piercing pain. It feels like my brain is being squeezed. It causes extreme sensitivity to light and sound and horrible nausea, said Knigge. There have been times when I have been at a pain level of 6 or higher for approximately 25 days out of the month. They impact my quality of life.