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Scientists shrink pancreatic tumors by starving their cellular neighbors

 E-Mail IMAGE: The scientists found elevated levels of cell drinking, or macropinocytosis (green) in the stromal cells exposed to a low-nutrient environment (right), compared to normal nutrient levels that surround healthy tissue. view more  Credit: Sanford Burnham Prebys Medical Discovery Institute Scientists at Sanford Burnham Prebys Medical Discovery Institute demonstrated for the first time that blocking cell drinking, or macropinocytosis, in the thick tissue surrounding a pancreatic tumor slowed tumor growth providing more evidence that macropinocytosis is a driver of pancreatic cancer growth and is an important therapeutic target. The study was published in Now that we know that macropinocytosis is revved up in both pancreatic cancer cells and the surrounding fibrotic tissue, blocking the process might provide a double whammy to pancreatic tumors, says Cosimo Commisso, Ph.D., associate professor and co-director of the Cell and Molecular Biology of C

Researchers study impact of pandemic cancer screening pause

BREITBART 18 Mar 2021 Months after mammograms, colonoscopies and other routine cancer screenings were suspended because of the pandemic, researchers are studying the impact Researchers study impact of pandemic cancer screening pauseBy MARILYNN MARCHIONEAP Chief Medical WriterThe Associated Press John Abraham’s colonoscopy was postponed for several months because of the pandemic. When he finally got it, doctors found a growth too big to be removed safely during the scope exam. He had to wait several weeks for surgery, then several more to learn it had not yet turned cancerous. “I absolutely wonder if I had gotten screened when I was supposed to have, if this would have been different” and surgery could have been avoided, said Abraham, a mortgage banker in Peoria, Illinois.

Cancer mutations insight could boost detection and personalize treatments

Cancer mutations insight could boost detection and personalize treatments
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NANOBIOTIX Reports Full Year 2020 Financial Results and Highlights Operational Progress

NANOBIOTIX Reports Full Year 2020 Financial Results and Highlights Operational Progress Substantial progress in priority development pathway in head and neck cancer with clinical registration plan announced, Fast Track designation granted by US Food and Drug Administration, and new data from phase I dose expansion showing 83% objective response rate in primary lesion. First clinical data reported phase I immuno-oncology trial showing conversion of anti-PD-1 non-responders to responders. Extended global capital markets presence with a successful Nasdaq IPO that provided gross proceeds of €93.5 million ($113.3 million). Cash, cash equivalents, and short-term investments were €119.2 million at December 31, 2020, supporting robust development plans into the second quarter of 2023.

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