A Greek researcher in Britain has developed an innovative artificial intelligence system that diagnoses dementia before the onset of the first symptoms.
You're in the car, with Sirius XM tuned to Deep Cuts. The Holllies' 1967 song "Carrie Anne" is playing. As you absently trill along with "People live and learn but you're still learning" while waiting for the light to change, you realize you know every word of the lyrics. And it's hardly the only decades-old rock tune you can sing along with, line by line.
HIV-positive people with severe immunosuppression, APOE4 gene may have increased risk for dementia
People living with the human immunodeficiency virus (HIV) who have a history of severe immunosuppression and at least one copy of the Alzheimer s disease-related gene variant APOE4, might see a compounded adverse effect on the circuitry that impacts memory. This could eventually lead to an increased risk for dementia after age 65, according to Georgetown University Medical Center investigators and colleagues.
The researchers used MRI scans to examine the brain, with a focus on two regions - the hippocampus, which is critical for memory and is often affected in Alzheimer s disease, and the caudate nucleus, which sits deep in the center of the brain and is often affected in people with HIV. Based on the MRI images, they found that connectivity between the two regions was affected by APOE4 in people with HIV. A history of severe immunosuppression further exacerbated the impact of APOE4.
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WASHINGTON (Feb. 22, 2021) - People living with the human immunodeficiency virus (HIV) who have a history of severe immunosuppression and at least one copy of the Alzheimer s disease-related gene variant APOE4, might see a compounded adverse effect on the circuitry that impacts memory. This could eventually lead to an increased risk for dementia after age 65, according to Georgetown University Medical Center investigators and colleagues.
The researchers used MRI scans to examine the brain, with a focus on two regions - the hippocampus, which is critical for memory and is often affected in Alzheimer s disease, and the caudate nucleus, which sits deep in the center of the brain and is often affected in people with HIV. Based on the MRI images, they found that connectivity between the two regions was affected by APOE4 in people with HIV. A history of severe immunosuppression further exacerbated the impact of APOE4.
Interhemispheric connectivity important for integration of speech sound information, study shows
When we listen to speech sounds, the information that enters our left and right ear is not exactly the same. This may be because acoustic information reaches one ear before the other, or because the sound is perceived as louder by one of the ears. Information about speech sounds also reaches different parts of our brain, and the two hemispheres are specialized in processing different types of acoustic information. But how does the brain integrate auditory information from different areas?
To investigate this question, lead researcher Basil Preisig from the University of Zurich collaborated with an international team of scientists. In an earlier study, the team discovered that the brain integrates information about speech sounds by balancing the rhythm of gamma waves across the hemispheres a process called oscillatory synchronization .