Researchers develop a technique to produce transplantable livers in the laboratory
April 5, 2021ScienceBlog.com
Researchers at the Human Genome and Stem Cell Research Center (HUG-CELL), hosted by the University of São Paulo’s Institute of Biosciences (IB-USP) in Brazil, have developed a technique to reconstruct and produce livers in the laboratory.
The proof-of-concept study was conducted with rat livers. In the next stage of their research, the scientists will adapt the technique for the production of human livers in order in future to increase the supply of these organs for transplantation.
The study was supported by FAPESP and is reported in an article published in
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IMAGE: Discovery paves the way for the study of more potent molecules capable of directly destroying parasites with fewer adverse side-effects view more
Credit: CQMED
Brazilian researchers have managed to decipher the structure of a protein found in parasites that cause neglected tropical diseases, paving the way to the development of novel medications. Thanks to the discovery it will be possible to seek more potent molecules capable of destroying the pathogens directly, with fewer adverse side-effects for patients.
The study detailed the structural characteristics of the protein deoxyhypusine synthase (DHS), found in
Brugia malayi, one of the mosquito-borne parasites that cause elephantiasis, and in