Allelica s polygenic risk score data published in
Circulation
Halsin Partners
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Rome, Italy, March 8, 2021 - Allelica, a leading genomics software company specialising in developing polygenic risk scores (PRS) for personalised medicine, today announced publication of a study in
Circulation (Vol. 143, Issue 10) showing that the effect of LDL cholesterol on a person s risk of having a heart attack depends on their genes. Using Allelica s proprietary PRS analysis software, the data showed that combining information on an individual s genetic risk of heart attack with their LDL level helps determine those at most risk from heart attack, including those potentially in need of treatment with statins or PCSK9 inhibitors. The PRS was also able to identify individuals eligible for therapeutic intervention based on current guidelines, which do not include polygenic risk, but who are in fact at low risk of heart attack based on their genes and LDL levels, so co
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-AGREEMENT ADVANCES EVOLUTION OF SYNTHETIC LUNG SURFACTANTS TO TREAT RESPIRATORY DISTRESS SYNDROME IN PREMATURE INFANTS IN LOW- AND MIDDLE-INCOME COUNTRIES-
LOS ANGELES (March 8, 2021) The Lundquist Institute (TLI) and The Bill & Melinda Gates Medical Research Institute (Gates MRI) executed a license agreement for TLI intellectual property covering a synthetic lung surfactant formulation to be developed for respiratory distress syndrome (RDS) for premature infants in Low- and Middle-Income countries (LMIC). TLI already maintains patents on this invention in the United States, Canada and Europe.
Newborns experiencing RDS must dramatically increase the effort to take each breath, due to lack of adequate, naturally-occurring surfactant production in their lungs. This deficiency of lung surfactant leads to fatigue, episodes of apnea, hypoxia, wasting, and potentially death if untreated. The standard of care is injecting naturally-occurring surfactant, normally animal-deriv
Credit: KIRSTY CHALLEN, B.SC., MBCHB, MRES, PH.D., LANCASHIRE TEACHING HOSPITALS, UNITED KINGDOM.
DES PLAINES, IL - A Boston violence intervention advocacy program is effectively engaging the client population that hospital-based violence intervention programs (HVIPs) have been designed to support. This is the conclusion of a study titled Boston Violence Intervention Advocacy Program: Challenges and Opportunities for Client Engagement and Goal Achievement, to be published in the March 2021 issue of
Academic Emergency Medicine (AEM), a journal of the Society for Academic Emergency Medicine (SAEM).
According to the study, HVIPs should consider which types of client needs prove most challenging to address and which novel strategies will engage vulnerable populations not typically targeted by intervention programs. These results speak to the difficulties of program attrition and the complexities of altering the life course for victims of violence.
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PHILADELPHIA Even before the COVID-19 pandemic, mental health issues have been on the rise across the nation, but many struggle to access the care they need. Collaborative care a proven approach for improving psychiatric care combats this issue by integrating mental health professionals into the primary care setting. Penn Medicine s collaborative care program, Penn Integrated Care (PIC), utilizes a centralized resource center to facilitate intake, triage, and referral management for all patients with mental health needs. A new study, published today in the
Annals of Family Medicine, suggests that this approach is effective and efficient for meeting the needs of a diverse group of patients with the full range of mental health conditions seen in primary care.
What The Study Did:
Researchers assessed the number of hospital admissions for noncommunicable diseases (abnormal tissue growths, metabolic diseases, cardiovascular diseases and musculoskeletal diseases) in São Paulo, Brazil, between January and June last year compared with the corresponding periods in the previous three years.
Authors:
Fernando Adami, Ph.D., of the Laboratório de Epidemiologia e Análise de Dados, Centro Universitário Saúde ABC in São Paulo, Brazil, is the corresponding author.
To access the embargoed study:
Visit our For The Media website at this link