January 22, 2021
A significant proportion of real-world patients with severe aortic stenosis and low surgical risk have an additional valvular or CV condition that was never accounted for in pivotal trials of TAVI versus SAVR and that requires a serious discussion by the heart team, Canadian research shows.
In the study of primarily low-risk patients who underwent SAVR between 2000 and 2019, 40.8% had at least one of the following conditions: non-tricuspid aortic valve (NTAV), severe coronary artery disease (SevCAD), concomitant mitral/tricuspid valve (CMTV), or concomitant ascending aorta replacement (CAAR). All four of those patient subgroups were routinely excluded from RCTs of TAVI compared with SAVR.
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Data analysis reveals a second decline in cardiovascular admissions during COVID-19 pandemic
Data analysis is revealing a second sharp drop in the number of people admitted to hospital in England with acute heart failure or a heart attack.
The decline began in October, as the numbers of COVID-19 infections began to surge ahead of the second lockdown, which came into force in early November.
The findings, from a research group led by the University of Leeds, have been revealed in a letter to the Journal of the American College of Cardiology.
The decline - 41 percent fewer people attending with heart failure and 34 percent with a heart attack compared to pre-pandemic levels - is approaching the size of that observed during the first wave of the pandemic. The researchers believe the drop in people seeking emergency medical help for cardiovascular emergencies in the first wave of the pandemic may have contributed to more than 2,000 excess deaths in England and Wales.
Date Time
Heart patients ‘fearful’ of seeking medical help amid COVID crisis
Data analysis by researchers at the University of Leeds is revealing a second sharp drop in the number of people admitted to hospital in England with acute heart failure or a heart attack.
The decline may be linked to patients being reluctant to go to hospital out of a fear of contracting COVID-19.
“…if patients delay or avoid treatment, they will suffer life-limiting complications or they will die.”
Patient numbers declined sharply during the first wave of the pandemic and although they did rebound, they never returned to the levels seen before the pandemic. They began to fall sharply again as the numbers of COVID-19 infections began to surge ahead of the second lockdown in early November 2020.