LSU Health Shreveport
SHREVEPORT â A team of scientists and clinicians at LSU Health Shreveport, collaborating across the Centers for Brain Health and Cardiovascular Diseases and Sciences, had their groundbreaking findings on a new blood biomarker for Alzheimerâs disease and related dementia published in the prestigious âAlzheimerâs & Dementia, The Journal of the Alzheimerâs Associationâ. LSUHS faculty Drs. Elizabeth Disbrow, Chris Kevil, Steve Alexander, and Karen Stokes were joined by colleagues from the Vascular Medicine Institute at the University of Pittsburg Medical Center and the Department of Computer Science at Louisiana State University in Shreveport.
There is growing appreciation for the important role cerebrovascular disease plays in the development of Alzheimerâs disease and related dementias (ADRD). The newly identified plasma biomarker for ADRD, hydrogen sulfide, is already a known biomarker for cardiovascular disease. The team use
Collaborative research between the University of Kentucky and the University of Southern California (USC) suggests that a noninvasive neuroimaging technique may index early-stage blood-brain barrier (BBB) dysfunction associated with small vessel disease (SVD). Cerebral SVD is the most common cause of vascular cognitive impairment, with a significant proportion of cases going on to develop dementia. BBB dysfunction represents a promising early marker of SVD because the BBB regulates a number of important metabolic functions, including clearance of toxic brain substances.
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LEXINGTON, Ky. (May 5, 2021) - Collaborative research between the University of Kentucky (UK) and University of Southern California (USC) suggests that a noninvasive neuroimaging technique may index early-stage blood-brain barrier (BBB) dysfunction associated with small vessel disease (SVD). Cerebral SVD is the most common cause of vascular cognitive impairment, with a significant proportion of cases going on to develop dementia. BBB dysfunction represents a promising early marker of SVD because the BBB regulates a number of important metabolic functions, including clearance of toxic brain substances.
Advanced BBB dysfunction can be detected with neuroimaging measures such as positron emission tomography (PET) scanning and dynamic contrast-enhanced (DCE) MRI. However, these methods require exposure to radiation or contrast agents and may only detect moderate to advanced stages of BBB tissue disruption. The UK-USC study used a novel, noninvasive MRI method called diffusion
Study: Middle-aged people who sleep less than than 7 hours nightly may have increased risk of dementia
By Catherine Park
A new study shows that people with dementia are at an increased risk of contracting COVID-19.
Middle-aged people who get less than seven hours of sleep a night could be at higher risk for developing dementia later in life, according to a recent study.
The study, highlighted by the National Institute of Health, was led by Dr. Séverine Sabia of Inserm and University College London and published in Nature Communications on April 20, followed participants for less than a decade who were in their 50s, 60s and 70s.