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Scientists develop a simple, noninvasive diagnostic solution for Alzheimer s disease

Scientists develop a simple, noninvasive diagnostic solution for Alzheimer s disease An international research team led by HKUST has developed a simple but robust blood test from Chinese patient data for early detection and screening of Alzheimer s disease (AD) for the first time, with an accuracy level of over 96%. Currently, doctors mainly rely on cognitive tests to diagnose a person with AD. Besides clinical assessment, brain imaging and lumbar puncture are the two most commonly used medical procedures to detect changes in the brain caused by AD. However, these methods are expensive, invasive, and frequently unavailable in many countries. Now, a team led by Prof. Nancy IP, Vice-President for Research and Development at HKUST, has identified 19 out of the 429 plasma proteins associated with AD to form a biomarker panel representative of an AD signature in the blood. Based on this panel, the team has developed a scoring system that distinguishes AD patients from healthy people

Hong Kong researchers develop Alzheimer s disease blood test, paving way for mass screening and early detection

June 29, 2021 Scientists in Sweden and Britain now believe blood tests can be used to predict Alzheimer. Reuters Researchers at Hong Kong University of Science and Technology have developed a blood test that can detect Alzheimer’s disease in as little as two days with more than 96 per cent accuracy, allowing early detection and screening of dementia for the first time. Led by world-renowned neuroscientist Professor Nancy Ip Yuk-yu, vice-president for research and development at the university, the team developed an ultra-sensitive detection method with which it identifies 19 out of the 429 plasma proteins associated with Alzheimer’s disease (AD). “With the advancement of ultra-sensitive blood-based protein detection technology, we have developed a simple, non-invasive and accurate diagnostic solution for AD, which will greatly facilitate population-scale screening and staging of the disease,” Ip said on Monday.

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