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Structure of BRCA2 protein complex critical for DNA repair solved

The initials BRCA2 may be best known for a gene associated with many cases of breast cancer, and the protein encoded by the BRCA2 gene is critical to repairing breaks in DNA.

Vastra gotalands lanRitvija agrawalJayakrishnan nandakumarDevon pendleburyEmily hendersonUniversity of gothenburgArgonne national laboratoryNature structuralMolecular biologyBrca2 geneBreast cancerMolecular biologyX rayஎமிலி ஹென்டர்சன்பல்கலைக்கழகம் ஆஃப் கோடெந்ப்ர்க்ஆர்கோன் தேசிய ஆய்வகம்

Researchers solve structure of BRCA2 protein complex important in DNA repair

Researchers solve structure of BRCA2 protein complex important in DNA repair
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Vastra gotalands lanHiroki shibuyaRitvija agrawalJayakrishnan nandakumarDevon pendleburyDepartment of chemistryUniversity of gothenburgArgonne national laboratoryNature structuralMolecular biologyதுறை ஆஃப் வேதியியல்பல்கலைக்கழகம் ஆஃப் கோடெந்ப்ர்க்ஆர்கோன் தேசிய ஆய்வகம்இயற்கை கட்டமைப்புமூலக்கூறு உயிரியல்

Giant Amoeba-Infecting Viruses Rely on DNA-Packing Proteins

Giant Amoeba-Infecting Viruses Rely on DNA-Packing Proteins
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United statesCity ofUnited kingdomTobias warneckeYamini dalalNational cancer instituteImperial college londonUniversity of colorado boulderMarseille universityHoward hughes medical institute investigator karolin lugerNature structuralMolecular biologyColorado boulderAix marseille universityNational cancerஒன்றுபட்டது மாநிலங்களில்

Enzym schaltet virusähnliche Sequenzen stumm

Enzym schaltet virusähnliche Sequenzen stumm
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Methyltransferasen dnmtBioinformatikerin heleneAleksandr meissnerChuck haggertySchwesterenzym dnmtDuring the developmentOther researchResearch hasNew publicationOne sideMolecular geneticsNew workNature structuralMouse specificallyHas turnedTransposons have

Ion channel conserved in coronaviruses a potential new drug target for COVID therapeutics

Ion channel conserved in coronaviruses a potential new drug target for COVID therapeutics Much of the research on the coronavirus disease 2019 (COVID-19) therapeutics has been focused on essential structures such as the virus-encoded spike protein, main proteases, as well as ribonucleic acid (RNA) polymerase proteins. Obtaining high-resolution analyses of these structures provides a mechanical insight into their function and assists in using these structures as targets in the development of both vaccines and anti-viral therapeutics. A better understanding of these structures will also allow scientists to effectively overcome the challenges presented by emerging variants and the consequent rise in infection rates that follow. To this end, a recent study published in

Nature structuralMolecular biologydiscussesஇயற்கை கட்டமைப்பு