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South32 Hermosa Community Fund Grants Program – United States

South32 Hermosa Community Fund Grants Program – United States 135SHARES Deadline: 29-Jan-21 The South32 Hermosa Community Fund, a fund of the Community Foundation for Southern Arizona and its geographic affiliate, the Santa Cruz Community Foundation, supports nonprofit organizations based in Santa Cruz County. Supported areas include arts, culture and history, environment, health and welfare, recreation, and civic enhancement. South32 is a globally diversified mining and metals company.  The South32 Hermosa project is located in the northern section of the Patagonia Mountains in Santa Cruz County. Amount: Up to $60,000 will be available each cycle; requests up to $10,000 will be considered. Only one application will be accepted per organization per year (unless otherwise approved by S32 Fund).

Physical frailty syndrome: a cacophony of multisystem dysfunction

In the inaugural issue of the journal Nature Aging a research team led by aging expert Linda P. Fried, MD, MPH, dean of Columbia University Mailman School of Public Health, synthesizes converging evidence that the aging-related pathophysiology underpinning the clinical presentation of phenotypic frailty (termed as physical frailty here) is a state of lower functioning due to severe dysregulation of the complex dynamics in our bodies that maintains health and resilience. When severity passes a threshold, the clinical syndrome and its phenotype are diagnosable. This paper summarizes the evidence meeting criteria for physical frailty as a product of complex system dysregulation. This clinical syndrome is distinct from the cumulative-deficit-based frailty index of multimorbiditys. The paper is published online here.

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