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16% Certain financial information for 2021 and 2020 is presented on both a reported and a non-GAAP basis. Some numbers in this press release may not add due to rounding. Reported results were prepared in accordance with U.S. generally accepted accounting principles (GAAP) and include all revenue and expenses recognized during the periods. Non-GAAP measures reflect adjustments for the items described in the reconciliation tables later in the release. Beginning in 2021, non-GAAP measures exclude gains and losses on investments in equity securities and 2020 amounts have been reclassified for comparability. The company s 2021 financial guidance is being provided on both a reported and a non-GAAP basis. The non-GAAP measures are presented to provide additional insights into the underlying trends in the company s business.

Molly mccullyEdgardo hernandezDiogo rauAlonzo weemsEli lillyDavida ricksKevin hernKimberlyh johnsonPrecision biosciences incVir biotechnology incArthritis advisory committeeBoehringer ingelheimCompensation committeeResearch developmentPfizer incTherapeutics inc