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Children less likely to spread SARS-CoV-2 than adults
A study conducted by researchers in Canada suggests that children may be less likely than adults to spread the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19).
As recently reported in
The Canadian Medical Association Journal (CMAJ), the study found that samples taken from 175 children aged 17 years or younger were about half as likely to contain culturable viruses than samples taken from adults.
Furthermore, when SARS-CoV-2 was successfully cultured, a significantly less viable virus was present in samples from children than from adults.
The team from Cadham Provincial Laboratory in Winnipeg, Manitoba, says the findings suggest that children do not appear to be the main drivers of SARS-CoV-2 transmission, which has important public health and clinical implications.
In a recent bioRxiv preprint, the large team of researchers evaluated a SARS-CoV-2 Spike receptor-binding domain ferritin nanoparticle protein vaccine (RFN) in a nonhuman primate challenge model. This study addresses the need for a next-generation, efficacious vaccine with an increased pan-SARS breadth of coverage.
Beyond vaccination, the broad-spectrum antiviral medication remdesivir has robust clinical evidence and is known as the best antiviral treatment to reduce severe COVID-19 infection in hospitalized patients. Research led by John F.X. Diffley of the Chromosome Replication Laboratory suggests a potential therapeutic target for treatment development is the viral RNA cap methyltransferases, essential for viral protein translation and immune evasion.
Coronavirus | Curfew in Maharashtra for 15 days from April 14, says Uddhav Thackeray
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Uddhav Thackeray refrained from terming the new curbs as a lockdown.
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Maharashtra Chief Minister Uddhav Thackeray addresses the people of the State on April 13, 2021 on coronavirus restrictions. Photo: Twitter/@CMOMaharashtra
Uddhav Thackeray refrained from terming the new curbs as a lockdown.
Maharashtra Chief Minister Uddhav Thackeray on Tuesday announced a “mini-lockdown” in the State from 8 p.m. on April 14 for the following 15 days. The State government also announced a financial package of ₹5,400 crore to help individuals who would be directly impacted due by the restrictions and closure of business.