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UNSW medical researchers have found a way to starve pancreatic cancer cells and ‘disable’ the cells that block treatment from working effectively. Their findings in mice and human lab models – which have been 10 years in the making and are about to be put to the test in a human clinical trial – are published today in
Cancer Research, a journal of the American Association for Cancer Research.
“Pancreatic cancer has seen minimal improvement in survival for the last four decades – and without immediate action, it is predicted to be the world’s second biggest cancer killer by 2025,” says senior author Associate Professor Phoebe Phillips from UNSW Medicine & Health.
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Credit: UNSW Sydney
UNSW medical researchers have found a way to starve pancreatic cancer cells and disable the cells that block treatment from working effectively. Their findings in mice and human lab models - which have been 10 years in the making and are about to be put to the test in a human clinical trial - are published today in
Cancer Research, a journal of the American Association for Cancer Research. Pancreatic cancer has seen minimal improvement in survival for the last four decades - and without immediate action, it is predicted to be the world s second biggest cancer killer by 2025, says senior author Associate Professor Phoebe Phillips from UNSW Medicine & Health.
Study may lead to new treatment for incurable brain cancer in children
Research by Australian scientists could pave the way to a new treatment for a currently incurable brain cancer in children called Diffuse Intrinsic Pontine Glioma, or DIPG. Affecting about 20 children in Australia each year, DIPG is a devastating disease with an average survival time of just nine months after diagnosis.
The research, led by scientists at Children s Cancer Institute and published this week in the international journal,
Cell Reports, offers an exciting new therapeutic approach for the treatment of DIPG by using a new anti-cancer drug.
The new drug, CBL0137, is an anti-cancer compound developed from the antimalarial drug quinacrine. The researchers found that CBL0137 directly reverses the effects of the key genetic drivers in DIPG, and has a profound effect against DIPG tumor models.
A little girl lives on through one big wish
A little girl lives on through one big wish
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Former New York Giants quarterback Eli Manning, left, visited the Make-a-Wish New Jersey headquarters in Monroe on April 13 to fulfill a wish of the late Penelope, a young girl whose memory is being honored with a donation to Tackle Kids Cancer. PHOTO COURTESY OF MAKE-A-WISH NEW JERSEY
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Penny s parents, Cassandra and Jack, speak about their daughter during the April 13 private ceremony.PHOTO COURTESY OF MAKE-A-WISH NEW JERSEY
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Dr. Alfred Gillio, director of Children s Cancer Institute, Hackensack Meridian Children s Health, left to right; Joyce P. Hendricks, president and chief development officer, Hackensack Meridian Health Foundation; former New York Giants quarterback Eli Manning; Penelope s parents Jack Lindsay and Cassandra Izquierdo; and Make-A-Wish New Jersey President/CEO Tom Weatherall honor Penny with her wish to give back to other children durin