Many studies have investigated the benefits of vitamin D supplementation for MS, with mixed results.
A team led by Alexandrina Sartori, PhD, at São Paulo State University, Brazil, has been using experimental autoimmune encephalomyelitis (EAE), an animal model of MS, to show that administration of vitamin D during the preclinical phase of the disease could be prophylactic (preventive).
The preclinical phase of a disease is the period of time when symptoms are not yet apparent, but the disease is biologically present.
“We recently observed that an early intervention with [vitamin D], delivered 24 hours after experimental encephalomyelitis induction, prevented neurodegeneration,” the researchers wrote.
in vitro and
in vivo (APPswe/PS1dE9 mouse model of Alzheimer’s disease) experiments that show increased mast cell hemichannel activity after treatment with amyloid peptide (Ab
25–35), with subsequent degranulation response and enhanced histamine release [2]. The number of mast cells in hippocampal and cortical areas increased drastically even before amyloid plaque deposits became evident, suggesting that mast cells are one of the first brain cells to recognize and respond to amyloid peptides, and thus may play a critical role in the onset and progression of Alzheimer’s disease. Treatment with masitinib was shown to totally prevent the amyloid-induced hemichannel-dependent mast cell activity in bone marrow-derived mast cells and brain mast cells. The authors concluded that hemichannel expressed by mast cells might serve as a molecular target with which to develop therapeutic treatments that could delay the onset and progression of Alzheimer’s disease.
AB Science announces that a new independent publication confirms the role of masitinib as a potential therapy in neurodegenerative disorders including Alzheimer s Disease benzinga.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from benzinga.com Daily Mail and Mail on Sunday newspapers.
Fusarium wilt, caused by a soilborne fungus, is one of the most damaging diseases of watermelons worldwide. Since it was discovered in 1894, itâs been a battle for producers to manage through crop rotation and chemical fungicides.
The fungus is persistent in both seedless and seeded varieties, and its spores can last for many years in the soil. While there are some watermelon varieties with known resistance, they are not resistant to all strains of the pathogen.
University of Georgia researchers have now developed a faster way to detect the diseaseâs presence and determine the races, or groups of strains, of the pathogen Fusarium oxysporum f. sp. niveum (FON) that cause the disease.
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Eat These 5 Foods to Support Your Immune System
Yes, what you eat can help keep you healthy. Hinterhaus ProductionsGetty Images
Vitamins and supplements are highly useful tools for a lot of folks looking for some immune system support through cold and flu season and beyond. But they are just that tools. They are not a foolproof solution to stay healthy. The best way to achieve that goal, and support a strong immune system, is by packing your diet with whole, nutrient-dense foods.
Eating a varied diet that includes foods rich in immune-boosting nutrients think vitamins A, D, E, C, selenium, zinc, and antioxidants combined with proper sleep and exercise can help keep illness at bay. Certain fats, particularly omega-3 fatty acids, have also been associated with immune health benefits, according to a review published in the high impact factor