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Scientists have isolated a set of promising, tiny antibodies or nanobodies against the novel coronavirus from a llama, some of which may help prevent the infection.
Preliminary results, published in the journal Scientific Reports, suggest that the nanobody appears to work equally well in either liquid or aerosol form, suggesting it could remain effective after inhalation.
The researchers from the National Institutes of Health (NIH) in the US said at least one of these nanobodies, called NIH-CoVnb-112, could prevent infections and detect virus particles by grabbing hold of the spike proteins of SARS-CoV-2, which causes Covid-19. We hope that these anti-Covid-19 nanobodies may be highly effective and versatile in combating the coronavirus pandemic, said David L. Brody, who is also a professor at Uniformed Services University for the Health Sciences.
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The National Institutes of Health researchers have recently isolated a set of potential and tiny antibodies, also called nanobodies as shields from SARS-CoV-2, reportedly produced by a llama Cormac.
Initial findings published in Scientific Reports suggest that at least one of the said nanobodies, also known as NIH-CoVnb-112, could prevent infections and identify virus particles by grabbing hold of SARS-CoV-2 spike proteins.
Additionally, the nanobody seemed effective equally well in either aerosol or liquid form, suggesting it could stay effective following inhalation. SARS-CoV-2 is a virus that causes COVID-19.
The research, led by two neuroscientists, Thomas J. or TJ Esparza, BS, and David Brody, MD, Ph.D., is working in a brain imaging laboratory at the National Institute of Neurological Disorders Stroke or NIND of the NIH.
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IMAGE: NIH scientists showed that anti-COVID-19 nanobodies from a llama may be an effective tool in the battle against the COVID-19 virus. view more
Credit: Courtesy of Brody lab NIH/NINDS.
National Institutes of Health researchers have isolated a set of promising, tiny antibodies, or nanobodies, against SARS-CoV-2 that were produced by a llama named Cormac. Preliminary results published in
Scientific Reports suggest that at least one of these nanobodies, called NIH-CoVnb-112, could prevent infections and detect virus particles by grabbing hold of SARS-CoV-2 spike proteins. In addition, the nanobody appeared to work equally well in either liquid or aerosol form, suggesting it could remain effective after inhalation. SARS-CoV-2 is the virus that causes COVID-19.
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