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Issue of Equity Polar Capital Holdings plc ( Polar Capital or the Company ) announces that today 1,333,921 ordinary shares of 2.5 pence in the Company have been allotted and issued, each fully paid, under its block listing facility (Crystallisation of Preference Shares) in respect of the previously announced crystallisation of the Healthcare Opportunities Fund and the Polar Capital Global Healthcare Trust plc (RNS Number 6491D on 11 October 2018), and the partial crystallisation of the North American Fund (RNS Number 0949U on 20 November 2019). These shares will rank pari passu in all respects with the Company s existing shares in issue.   This issue comprises the fourth and final allotment of shares in respect of the Healthcare Opportunities Fund and the Polar Capital Global Healthcare Trust plc (1,218,022 shares) and the third allotment of shares in respect of the North American Fund (115,899 shares).

United statesAndrew buchananCharles farquharEd gascoigneStephen westgateJennifer renwickGavin rochussenPeel huntPolar capital global healthcareHealthcare opportunities fundAmerican fundPolar capital holdingsPolar capital partnersNumis securitiesCapital holdingsPreference shares